Europe has now emerged as the "epicentre" of the global coronavirus pandemic, says the head of the World Health Organization.
Expressing grave concern, Dr Tedros Adhanom Ghebreyesus urged countries to take aggressive measures, community mobilisation and social distancing to save lives, reports BBC.
He said, "Do not just let this fire burn."
There have been steep rises in the number of infections and deaths from Covid-19 across the European nations. Spain is now the worst affected after Italy.
On Friday, Spain reported a 50% jump in fatalities to 120. Infections increased to 4,200.
Prime Minister Pedro Sanchez says a state of emergency will come into effect there on Saturday for two weeks.
Controls are also being introduced at an increasing number of borders in Europe, in response to rapid spread of the virus.
More than 132,500 people have been diagnosed with Covid-19 in 123 countries around the world, according to the WHO.
The total number of deaths has reached about 5,000 - a figure Dr Tedros described as "a tragic milestone".
"Europe has now become the epicentre of the pandemic, with more reported cases and deaths than the rest of the world combined, apart from China," he said.
"More cases are now being reported every day than were reported in China at the height of its epidemic."
Europe's worst-affected country, Italy, has now reported more than 15,100 cases and 1,000 deaths. France has 2,860 cases, Germany 2,369 and there are now 798 confirmed infections in the UK.