Three advisers of Nepal's Prime Minister K.P. Sharma Oli said on Saturday they had tested positive for Covid-19, which has claimed the lives of 528 people in the country.
Oli's press, political and foreign affairs advisers told Reuters they had been infected and were isolating themselves.
An assistant working for Oli also tested positive, they added.
Oli has previously tested negative, but had yet to take a test after his associates tested positive, said press adviser Surya Thapa.
"The prime minister has been exercising extreme caution while meeting with people," Thapa told Reuters.
Oli's personal physician had earlier tested positive and is isolating herself, Thapa said.
Nepal's Covid–19 cases rose by 2,120 to 84,570 on Saturday, according to the health ministry.
Neighbouring India's coronavirus death toll passed 100,000 on Saturday, making it the third country to reach that milestone, after the United States and Brazil, and its epidemic shows no sign of abating.