Approximately once every minute and 40 seconds, a child or young person under the age of 20 was infected with HIV last year, says the UN Children's Fund (UNICEF).
In a latest report on Wednesday, the UN agency called upon the governments to "protect, sustain and accelerate" efforts to combat childhood HIV.
The report, styled "Reimagining a resilient HIV response for children, adolescents and pregnant women living with HIV", also warned that children are being left behind in the fight against HIV.
Prevention efforts and treatment for children remain some of the lowest amongst key affected populations, and in 2019, a little less than half of children worldwide did not have access to life-saving treatment, it said.
Nearly 320,000 children and adolescents were newly infected with Human Immunodeficiency Virus (HIV) and 110,000 children died of Acquired Immune Deficiency Syndrome (AIDS) last year.
"Children are still getting infected at alarming rates, and they are still dying from AIDS. This was even before COVID-19 interrupted vital HIV treatment and prevention services putting countless more lives at risk", said UNICEF Executive Director Henrietta Fore.
Life-saving HIV services hit by COVID-19
According to UNICEF, the COVID-19 pandemic has worsened inequalities in access to life-saving HIV) services for children, adolescents and pregnant mothers everywhere, and there are serious concerns that one-third of high HIV burden countries could face coronavirus-related disruptions.
"Even as the world struggles in the midst of an ongoing global pandemic, hundreds of thousands of children continue to suffer the ravages of the HIV epidemic", said Ms. Fore.
Data from the Joint UN Programme on HIV/AIDS (UNAIDS), cited in the report, shows the impact of control measures, supply chain disruptions, lack of personal protective equipment (PPE), and the redeployment of healthcare workers on HIV services.
Paediatric HIV treatment and viral load testing in children in some countries fell by 50 to 70 per cent, and new treatment initiation by 25 to 50 per cent in April and May, coinciding with partial and full lockdowns to control the novel coronavirus.
Health facility deliveries and maternal treatment were also reported to have reduced by 20 to 60 per cent, maternal HIV testing and antiretroviral therapy (ART) initiation by 25 to 50 per cent, and infant testing services by approximately 10 per cent.
Though the easing of control measures and the strategic targeting of children and pregnant mothers have successfully led to a rebound of services in recent months, challenges remain, and the world is still far from achieving the global 2020 paediatric HIV targets, said UNICEF.
Despite some progress in the decades-long fight against HIV and AIDS, deep regional disparities persist among all populations, especially for children.
While the Middle East and North Africa region recorded 81 per cent paediatric ART coverage, only 46 per cent and 32 per cent were covered in Latin America and the Caribbean, West and Central Africa, respectively.
The South Asia region recorded 76 per cent coverage, Eastern and Southern Africa 58 per cent, and East Asia and the Pacific 50 per cent.