Mirazur, on the French Riviera, was crowned No.1 at the World's 50 Best Restaurants awards ceremony held in Singapore on Tuesday (June 25), lauded for its fresh and seasonal cuisine.
The three-Michelin-starred restaurant in Menton climbed to the top from third last year, replacing Italy's Osteria Francescana.
Mirazur's menu, which includes dishes like salt-crusted beetroot from the garden with caviar cream, is inspired by the sea, the mountains and produce from its own gardens, which cascade over three levels.
Its Argentine-born chef Mauro Colagreco said he felt like being "on the sky" after winning the award. He and his team accepted the prize carrying a banner that combined the flags of Argentina, France, Brazil and Italy.
Mexican chef Daniela Soto-Innes took home the award for the World's Best Female Chef 2019.
Launched in 2002, the 50 Best list has grown in prominence to rival the long-established Michelin star system. The ceremony in Singapore is the first to be held in Asia.