Former Bosnian Serb commander Ratko Mladic has lost his appeal against a 2017 conviction for genocide, war crimes and crimes against humanity.
The UN court upheld the life sentence for his role in the killing of around 8,000 Bosnian Muslim (Bosniak) men and boys in Srebrenica in 1995, reports the BBC.
The massacre, in an enclave supposed to be under UN protection, was the worst atrocity in Europe since World War Two.
It is not yet clear where Mladic will serve the rest of his sentence.
The five-person appeals panel found Mladic had failed to provide evidence to invalidate the previous convictions against him, although the presiding judge dissented on almost all counts.
However, the Appeals Chamber also dismissed the appeal brought by the prosecution, which had sought a second conviction against Mladic over crimes committed against Bosnian Muslims and Bosnian Croats in some other areas during the war.
The verdict was delayed by technical difficulties, which continued throughout the session.
Mladic had denounced the tribunal during his appeal hearing in August, calling it a child of Western powers. His lawyers had argued he was far away from Srebrenica when the massacre happened.